Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment
A. Hirbayashi, Y. Muramoto, T. Takenaga, Y. Tsunoda, M. Wakazaki, M. Sato, Y. Fujita-Fujiharu, N. Nomura, K. Yamauchi, C. Onishi, M. Nakano, K. Toyooka, T. Noda
This study identifies COPI as essential for SARS-CoV-2 virion transport from the ERGIC, showing that COPB2 depletion inhibits viral replication.
mBio · Jan 8, 2025Peer-reviewedMicrobiology