T. Noda

Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment

This study identifies COPI as essential for SARS-CoV-2 virion transport from the ERGIC, showing that COPB2 depletion inhibits viral replication.

Structural basis of Ebola virus nucleocapsid assembly and functions

This study determines the structure of the Ebola virus nucleocapsid using cryo-EM and identifies VP24's role in assembly and function.

Immediate impact of the 2021 harmful algal bloom in southeast Hokkaido on the rocky intertidal community and its spatial variation

This study examines the immediate effects of a 2021 harmful algal bloom on rocky intertidal species abundance and spatial variation in southeast Hokkaido.

Isogenic iPSC-derived proximal and distal lung-on-chip models: Tissue- and virus-specific immune responses in human lungs

The paper develops isogenic lung-on-chip models from iPSC-derived cells to study tissue-specific immune responses to SARS-CoV-2 and Influenza viruses.

Genome-scale CRISPR-Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection.

The paper identifies TRIM28, TRIM33, EHMT1, and EHMT2 as novel host factors involved in SARS-CoV-2 infection and shows that EHMT1/2 inhibition reduces viral growth and disease severity.

vRNA-vRNA interactions in influenza A virus HA vRNA packaging

The paper identifies direct RNA-RNA interactions between HA and PB2 vRNAs in influenza A virus that are critical for selective genome packaging and viral replication.

LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice

This study identifies LRRC23 as a conserved component of the radial spoke complex in mouse sperm, essential for flagellar motility and male fertility but not ciliary function.

Next generation infection prevention clothing: Non-woven Fabrics Coated with Cranberry Extracts Capable of Inactivating Enveloped Viruses such as SARS-CoV-2 and Multidrug-resistant Bacteria

This paper develops non-woven fabrics coated with cranberry extracts that inactivate SARS-CoV-2, phage phi 6, and multidrug-resistant bacteria, validated using a C. elegans model.

Antiviral face mask functionalized with solidified hand soap: low-cost infection prevention clothing against enveloped viruses such as SARS-CoV-2

This paper describes an antiviral face mask made with solidified hand soap-coated fabric that inactivates enveloped viruses like SARS-CoV-2 within one minute and is non-toxic to human cells.

Structural insight into Marburg virus nucleoprotein-RNA complex formation

This study determines the structure of the Marburg virus NP-RNA complex using cryo-EM, revealing conserved residues critical for nucleocapsid formation and RNA synthesis between MARV and EBOV.

Influenza virus ribonucleoprotein complex formation occurs in the nucleolus

This study identifies the nucleolus as the site of vRNP formation and vRNA replication in influenza virus-infected cells.

Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells

This study uses ACE2-expressing human iPS cells to model SARS-CoV-2 infection and shows sex-based differences in viral production.

Protective face mask filter capable of inactivating SARS-CoV-2, and methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis

This paper develops a face mask filter with a biofunctional coating that inactivates SARS-CoV-2 and methicillin-resistant bacteria within one minute of contact.

Serine-arginine protein kinase 1 regulates Ebola virus transcription

This study identifies SRPK1 and SRPK2 as kinases that phosphorylate VP30, a key transcription factor for Ebola virus, and shows that disrupting this interaction impairs viral replication.

Microtubule-dependent transport of arenavirus matrix protein demonstrated using live-cell imaging microscopy.

The paper uses live-cell imaging to show that arenavirus matrix proteins are transported via microtubules, with LCMV serving as a safe model for studying LASV-related mechanisms.

A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages

This study identifies a defect in Influenza A virus particle assembly in primary human macrophages, specifically in HA-M2 association, which is reversible by disrupting actin polymerization.