Author

K. Yeung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Farfel· 1 shared A. Kennedy· 1 shared A. N. Michi· 1 shared B. A. Parker· 1 shared C. Hinze· 1 shared C. Lloyd· 1 shared C. T. Orozco· 1 shared D. Giovacchini· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Farfel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment

J. Reina, Q. Vallmajo-Martin, J. Ning, A. N. Michi, K. Yeung, G. M. Wahl, T. Hunter

This study shows that LHPP promotes TNBC growth and metastasis by altering the tumor microenvironment and chemokine signaling.

bioRxiv · Apr 19, 2024Cancer Biology

Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80 / PD-L1 interaction

M. A. Robinson, A. Kennedy, C. T. Orozco, H.-C. Chen, E. A. Waters, D. Giovacchini, K. Yeung, L. Filer, C. Hinze, C. Lloyd, S. Dovedi, D. Sansom

This paper shows that rigid, bivalent CTLA-4 binding to CD80 disrupts the cis CD80/PD-L1 interaction, promoting PD-L1 availability through orientation and cross-linking.

bioRxiv · Apr 19, 2024 · PreprintImmunology

Growth Signaling Autonomy in Circulating Tumor Cells Aids Metastatic Seeding

S. Sinha, A. Farfel, K. E. Luker, B. A. Parker, K. Yeung, G. D. Luker, P. Ghosh

This study defines the transcriptome, proteome, and phenome of growth signaling autonomy in breast cancer cells and shows its role in metastatic progression and drug resistance.

bioRxiv · Dec 2, 2022Cancer Biology