Author

Kai Chen

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Aishe Kurti· 1 shared Akhilesh PandeyiD· 1 shared Axel D. MenesesiD· 1 shared Benjamin J. MaddeniD· 1 shared Cassandra L. RosenbergiD· 1 shared Chenyang WangiD· 1 shared Chia‐Chen LiuiD· 1 shared Cristine M. CharlesworthiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Aishe Kurti

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Biodegradation of the endocrine-disrupting compound bisphenol F by Sphingobium yanoikuyae DN12

Ruomu Chen, Yutian Gan, Wanting Huang, Chenyang Wang, Junhong Ge, Yuanyuan Cheng, Wenjing Qiao, Jiandong Jiang, Kai Chen

This study isolates a BPF-degrading Sphingobium strain, identifies key enzymes in its degradation pathway, and elucidates their catalytic mechanisms.

Applied and Environmental Microbiology · Nov 6, 2025Peer-reviewedMicrobiology

TREM2-H157Y Increases Soluble TREM2 Production and Reduces Amyloid Pathology

Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia‐Chen Liu, Joshua A. Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel D. Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, , Guojun Bu

This study shows that the TREM2-H157Y mutation increases soluble TREM2 and reduces amyloid pathology in mice, suggesting a potential protective effect against Alzheimer's disease.

Molecular Neurodegeneration · Jan 31, 2023Peer-reviewedNeuroscience