Early-Life Wildfire Smoke Exposure Is Associated with Long-Term Systemic Immune Remodeling and Epigenetic Reprogramming
Cora E. Layman, David Morrow, Taylor J. Caron, Kandace J. Wheeler, Brett A. Davis, Paige Bergstrom, Katinka A. Vigh‐Conrad, Tanner J. Anderson, GW McElfresh, Kirstin N. Sterner, Baptiste Sadoughi, Noah Snyder‐Mackler, Scott G. Hansen, Benjamin N. Bimber, Christina Lancioni, , Mariam Okhovat
This study shows that early-life wildfire smoke exposure in rhesus macaques leads to long-term immune and epigenetic changes, including altered cytokine responses and accelerated epigenetic aging.
bioRxiv · Aug 29, 2026 · PreprintImmunology