Author

Kaneka Chheng

Murdoch Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew C. SteeriD· 2 shared Hannah R. C. FrostiD· 2 shared Joshua OsowickiiD· 2 shared Natalie CaltabianoiD· 2 shared Alana L. WhitcombeiD· 1 shared Brian Wilson-Boyd· 1 shared Catherine PittiD· 1 shared Catherine SatzkeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

Andrew C. SteerORCID

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2 papers

Recent·Most cited

Attenuated interferon signalling in alveolar epithelium limits resistance to Streptococcus pyogenes

Jeremy Wiyana, Declan L. Turner, Sahel Amoozadeh, Pooja Venkat, Katelyn Patatsos, Hannah R. C. Frost, Joshua Osowicki, Jasmyn Voss, Kaneka Chheng, Kristy I. Azzopardi, Natalie Caltabiano, Mark R. Davies, Mirana Ramialison, Catherine Satzke, Fernando Jaime Rossello, , Rhiannon B. Werder

This study compares S. pyogenes infection responses in airway and alveolar epithelial cells, finding that alveolar cells show higher cell death and a pro-inflammatory response without cytokine secretion, and that IFN-β treatment reduces infection.

bioRxiv · Apr 15, 2026 · PreprintMicrobiology

Antibody responses against bacterial glycans affinity mature and diversify in germinal centers.

Holly A. Fryer, Catherine Pitt, Hannah R. C. Frost, Nitika Kandhari, Sean Byars, Pailene S. Lim, Rhiannon L. Fettes, Reece M. Lovett, Trang T. Nguyen, Kaneka Chheng, Natalie Caltabiano, Alana L. Whitcombe, Julianne Hamelink, Dean W. Andrew, Gordon Lloyd, , Danika Lea Hill

The paper shows that glycan-specific B cells undergo class-switching and diversification in germinal centers with age and infection, influencing vaccine design.

Immunity · Mar 1, 2026Peer-reviewedImmunology