Nitika Kandhari

ADSS1 is a suppressed metabolic control node in dystrophic skeletal muscle

The paper identifies ADSS1 as a suppressed metabolic control node in dystrophic muscle, showing its role in purine metabolism and its impact on inflammatory and adipogenic remodelling.

Antibody responses against bacterial glycans affinity mature and diversify in germinal centers.

The paper shows that glycan-specific B cells undergo class-switching and diversification in germinal centers with age and infection, influencing vaccine design.

Moderate-term dimethyl fumarate treatment reduces pathology of dystrophic skeletal and cardiac muscle in a mouse model

This study shows that moderate-term dimethyl fumarate treatment reduces dystrophic muscle pathology in a mouse model of Duchenne muscular dystrophy, with anti-inflammatory, anti-fibrotic, and anti-lipogenic effects.