BioengineeringMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewed
Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver
Brett Estes, Nisha Gandhi, Jessica R. Von Stetina…·Jenny Xie
This paper develops circular AAV vectors for DSB-free genomic integration in the liver, demonstrating seamless gene insertion in human hepatocytes and in vivo.
6 citations