ImmunologybioRxivPreprint
OLT1177 (Dapansutrile) inhibits Gasdermin D-dependent IL-1β Release and Pyroptotic Cell Death in Bone Marrow-derived Macrophages
Karl A. Pankratz, Masoom Raza, Jarren Ypil…·Shaikh Muhammad Atif
OLT1177 inhibits IL-1β release and pyroptotic cell death in LPS-treated BMDMs by blocking caspase-1 and GSDMD activation.
DOI 10.64898/2026.05.31.729061