Parental origin of transgene determines recombination efficiency in GFAP-creERT2 mice
Karmen Mah, Adam Roszczyk, Ashley E. Frakes
The paper shows that the parental origin of the hGFAP-creERT2 transgene affects recombination efficiency in mice, with paternal inheritance leading to robust recombination and maternal inheritance causing little to none.
G3 Genes Genomes Genetics · Jun 17, 2025Peer-reviewedNeuroscience