Author

Antoine E. Roux

Calico Life SciencesORCID 0000-0003-2041-4318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Cynthia J. KenyoniD· 3 shared Adam Roszczyk· 1 shared Ashley E. FrakesiD· 1 shared Carrie A. Sheeler· 1 shared Chunlian ZhangiD· 1 shared Daviana Menendez Escalera· 1 shared David G. HendricksoniD· 1 shared David R. KelleyiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Cynthia J. KenyonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 14, 2025

A FMRF-amide peptide that regulates cell non-autonomous protein homeostasis in C. elegans.

Carrie A. Sheeler, Jacqueline Y. Lo, Daviana Menendez Escalera…·Ashley E. Frakes

This study identifies FLP-17, a neuropeptide that mediates cell non-autonomous UPRER activation in C. elegans, protecting against ER stress and protein aggregation.

DOI 10.1101/2025.03.14.643343

C. elegansstatistical model

𝕏 PostBluesky

GenomicsCell ReportsPeer-reviewedAug 1, 2023

The complete cell atlas of an aging multicellular organism

Antoine E. Roux, Han Yuan, Katie Podshivalova…·David R. Kelley

This paper creates a single-cell atlas of aging in C. elegans, revealing cell-type specific aging patterns and identifying transcription factors that regulate aging rates.

110 citationstop 2%

C. elegansscRNA-seq

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Systems BiologyCell SystemsPeer-reviewedJun 10, 2022

Partial reprogramming restores youthful gene expression through transient suppression of cell identity

Antoine E. Roux, Chunlian Zhang, Jonathan S. Paw…·Jacob C. Kimmel

This study investigates how transient reprogramming affects somatic cell identity and aging in mice, finding that it can restore youthful gene expression but also suppress identity programs.

84 citationstop 2%

mousebulk RNA-seq

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