Author

Katherine E. Nimchuk

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jung‐Bum ShiniD· 2 shared Alban GaultieriD· 1 shared Andrea R. MerchakiD· 1 shared Brant E. IsaksoniD· 1 shared Caitlin M. PaveleciD· 1 shared Daniel CheniD· 1 shared Daniel J. FosteriD· 1 shared David W Archer· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Jung‐Bum ShinORCID

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2 papers

Recent·Most cited

Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target

Yugesh Kharel, Tao Huang, Kyle Dunnavant, Daniel J. Foster, George M. P. R. Souza, Katherine E. Nimchuk, Andrea R. Merchak, Caitlin M. Pavelec, Zuzanna J. Juśkiewicz, Simon S. Alexander, Alban Gaultier, Stephen B.G. Abbott, Jung‐Bum Shin, Brant E. Isakson, Wenhao Xu, , Kevin R. Lynch

This study evaluates a novel S1P transport blocker, SLF80821178, showing efficacy in multiple sclerosis without the cardiac side effects of SRMs, but with less lymphopenia and unchanged lymph S1P levels.

British Journal of Pharmacology · Feb 2, 2025Peer-reviewedPharmacology & Toxicology

Repair of Noise-Induced Damage to Stereocilia F-actin Cores is Facilitated by XIRP2

Elizabeth L. Wagner, Jun‐Sub Im, Stefano Sala, Maura I Nakahata, Terence E. Imbery, Sihan Li, Daniel Chen, Katherine E. Nimchuk, Yael Noy, David W Archer, Wenhao Xu, George T. Hashisaki, Karen B. Avraham, Patrick W. Oakes, Jung‐Bum Shin

The paper shows that XIRP2 facilitates repair of noise-induced damage to stereocilia F-actin cores in mouse auditory hair cells by enriching monomeric gamma-actin at damaged sites.

eLife · May 18, 2023Peer-reviewedNeuroscience