MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML
Neha Goveas, Claudia Waskow, Kathrin Arndt, Julian Heuberger, Qinyu Zhang, Dimitra Alexopoulou, Andreas Dahl, Walter Birchmeier, Konstantinos Anastassiadis, Adrian Francis Stewart, Andrea Kranz
This study shows that MLL1 is essential for intestinal stem cell maintenance and regulates the expression of JAML, a cell adhesion molecule critical for stem cell niche interactions.
bioRxiv · Nov 19, 2020 · PreprintGenetics