Adrian Francis Stewart

Non-catalytic role for MLL2 in controlling chromatin organisation and mobility during priming of pluripotent cells for differentiation

This study shows MLL2 stabilizes 3D chromatin loops during pluripotent cell differentiation without requiring its enzymatic activity.

The Rad52 superfamily as seen by AlphaFold

The paper uses AlphaFold to analyze the structure of Rad52 superfamily proteins across species, confirming their orthology and structural similarities.

Postnatal SETD1B is essential for learning and the regulation of neuronal plasticity genes

This study shows that SETD1B is crucial for learning and regulates neuronal plasticity genes in the postnatal brain through H3K4me3 modification.

MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML

This study shows that MLL1 is essential for intestinal stem cell maintenance and regulates the expression of JAML, a cell adhesion molecule critical for stem cell niche interactions.

MLL4 is required for the first embryonic collective cell migration whereas MLL3 is not required until birth

The paper investigates the distinct developmental roles of MLL3 and MLL4 in mice, finding MLL4 is critical for early embryonic migration while MLL3 is needed for lung maturation.