Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic recovery to cytotoxic stress
Qinyu Zhang, Anna Rydström, Isabel Hidalgo…·Alexandra Rundberg Nilsson
This study examines the long-term effects of medium-dose irradiation and 5-FU on hematopoietic stem cells and hematopoietic recovery in mice, finding that irradiation causes sustained impairments and selective depletion of MHC class II- HSCs.