Konstantinos Anastassiadis

This study shows MLL2 stabilizes 3D chromatin loops during pluripotent cell differentiation without requiring its enzymatic activity.

This study shows that MLL1 is essential for intestinal stem cell maintenance and regulates the expression of JAML, a cell adhesion molecule critical for stem cell niche interactions.

The paper investigates the distinct developmental roles of MLL3 and MLL4 in mice, finding MLL4 is critical for early embryonic migration while MLL3 is needed for lung maturation.

This study identifies that human axial progenitors generate trunk neural crest cells and defines their molecular signatures.

The paper investigates X-linked gene reactivation in mouse inner cell mass by analyzing epigenetic marks and transcription factors, finding differential reactivation speeds and mechanisms.