Author

Keifer Holcomb

Colorado School of Mines

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Nikki L. FarnsworthiD· 2 shared Ali Shilleh· 1 shared Amit SelaiD· 1 shared Andres Ocampo· 1 shared Ashton Fremin· 1 shared Austin Kratz· 1 shared Brisa PeñaiD· 1 shared Christine El-Dirani· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Nikki L. FarnsworthORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Laminin-511 protects pancreatic β-cells from cytokine-induced death through integrin-mediated pro-survival signaling and modulation of protein kinase C δ

Christine El-Dirani, Meghana Hosahalli Shivananda Murthy, Keifer Holcomb, Gwendolyn Gutierrez, Riley Starzel, Brisa Peña, Daewon Park, Richard K.P. Benninger, Nikki L. Farnsworth

This study shows laminin-511 protects β-cells from cytokine-induced death by activating Akt signaling and reducing PKCδ activity through membrane DAG modulation.

bioRxiv · Aug 5, 2026 · PreprintCell Biology

Peptide Coated Polycaprolactone-Benzalkonium Chloride Nanocapsules for Targeted Drug Delivery to the Pancreatic β-Cell

Jillian Collins, Jessie M. Barra, Keifer Holcomb, Andres Ocampo, Ashton Fremin, Austin Kratz, Jubril Olayinka Akolade, Julianna K. Hays, Ali Shilleh, Amit Sela, David J. Hodson, Johannes Broichhagen, Holger A. Russ, Nikki L. Farnsworth

This paper develops peptide-coated nanocapsules for targeted drug delivery to pancreatic β-cells, showing effective in vitro and in vivo targeting and cargo delivery.

ACS Applied Bio Materials · Sep 24, 2024Peer-reviewedBioengineering