Author

Ken-ichi Yamada

Kyushu University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Akihiro IkedaiD· 2 shared Greg Barrett-Wilt· 2 shared Martin‐Paul AgbagaiD· 2 shared Michael LandowskiiD· 2 shared Purnima Gogoi· 2 shared Richard S. BrushiD· 2 shared Ryo Hagimori· 2 shared Sakae Ikeda· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersPhysiology

Akihiro IkedaORCID

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2 papers

Recent·Most cited

DHA deficiency drives neural oxidized-lipid stress and microglial activation

Ryo Hagimori, Purnima Gogoi, Pawan Kumar Shahi, Ryoya Ueno, Greg Barrett-Wilt, Michael Landowski, Kazuya Oikawa, Madison Tytanic, Richard S. Brush, Jingyang Wei, Maya S. Guerriero, Gillian J. McLellan, Sakae Ikeda, Martin‐Paul Agbaga, Bikash Ranjan Pattnaik, , Akihiro Ikeda

This study shows that DHA deficiency causes lipid remodeling and microglial activation in mice, leading to oxidative stress and visual dysfunction, with APOE-dependent lipid disposal and galectin-3 involvement.

bioRxiv · Sep 28, 2026 · PreprintPhysiology

TMEM135 deficiency remodels hepatic lipid homeostasis and protein malonylation through a DHA-sensitive lipogenic program buffered by peroxisomal metabolism

Ryo Hagimori, Michael Landowski, Siyu Song, Purnima Gogoi, Richard S. Brush, Sarah M. Bonvicino, Greg Barrett-Wilt, Sakae Ikeda, Ken-ichi Yamada, Chi–Liang Eric Yen, Tetsuya Takimoto, Martin‐Paul Agbaga, Akihiro Ikeda

This study shows TMEM135 deficiency leads to a lipogenic state with increased monounsaturated fatty acids and DHA depletion, which is buffered by peroxisomal metabolism and can be reversed by fish oil.

bioRxiv · Jul 23, 2026 · PreprintCell Biology