Author

Greg Barrett-Wilt

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Akihiro IkedaiD· 2 shared Chi–Liang Eric YeniD· 2 shared Ken-ichi Yamada· 2 shared Martin‐Paul AgbagaiD· 2 shared Michael LandowskiiD· 2 shared Purnima Gogoi· 2 shared Richard S. BrushiD· 2 shared Ryo Hagimori· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersPhysiology

Akihiro IkedaORCID

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3 papers

Recent·Most cited

DHA deficiency drives neural oxidized-lipid stress and microglial activation

Ryo Hagimori, Purnima Gogoi, Pawan Kumar Shahi, Ryoya Ueno, Greg Barrett-Wilt, Michael Landowski, Kazuya Oikawa, Madison Tytanic, Richard S. Brush, Jingyang Wei, Maya S. Guerriero, Gillian J. McLellan, Sakae Ikeda, Martin‐Paul Agbaga, Bikash Ranjan Pattnaik, , Akihiro Ikeda

This study shows that DHA deficiency causes lipid remodeling and microglial activation in mice, leading to oxidative stress and visual dysfunction, with APOE-dependent lipid disposal and galectin-3 involvement.

bioRxiv · Sep 28, 2026 · PreprintPhysiology

TMEM135 deficiency remodels hepatic lipid homeostasis and protein malonylation through a DHA-sensitive lipogenic program buffered by peroxisomal metabolism

Ryo Hagimori, Michael Landowski, Siyu Song, Purnima Gogoi, Richard S. Brush, Sarah M. Bonvicino, Greg Barrett-Wilt, Sakae Ikeda, Ken-ichi Yamada, Chi–Liang Eric Yen, Tetsuya Takimoto, Martin‐Paul Agbaga, Akihiro Ikeda

This study shows TMEM135 deficiency leads to a lipogenic state with increased monounsaturated fatty acids and DHA depletion, which is buffered by peroxisomal metabolism and can be reversed by fish oil.

bioRxiv · Jul 23, 2026 · PreprintCell Biology

Dietary lipid is largely deposited in skin and rapidly affects insulating properties

Nick Riley, Ildikó Kasza, Isabel D. K. Hermsmeyer, Michaela E. Trautman, Greg Barrett-Wilt, Raghav Jain, Judith A. Simcox, Chi–Liang Eric Yen, Ormond A. MacDougald, Dudley W. Lamming, Caroline M. Alexander

The paper shows dietary lipid is deposited in skin, altering its thermal properties and energy regulation within days.

Nature Communications · May 16, 2025Peer-reviewedPhysiology