Author

Kenneth Rodriguez-Lopez

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Kevin L. ScruddersiD· 2 shared Philip Stewart LowiD· 2 shared Shalini T. Low-NamiD· 2 shared Suilan ZhengiD· 2 shared Suriya Selvarajan· 2 shared Bo HuangiD· 1 shared Bo HuangiD· 1 shared Francisco N. BarreraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Kevin L. ScruddersORCID

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2 papers

Recent·Most cited

CAR T cell cytotoxic responses are rapidly generated and sensitive to the unligated TCR

Kevin L. Scrudders, Suriya Selvarajan, Kenneth Rodriguez-Lopez, Weichuan Luo, Bo Huang, Suilan Zheng, Geoffrey H. Graff, Francisco N. Barrera, Philip Stewart Low, Shalini T. Low-Nam

This study investigates CAR T cell cytotoxic responses, showing they are sensitive to TCR interactions and can be modulated by inhibitory peptides.

bioRxiv · Jul 25, 2025 · PreprintImmunology

A mechanistic model for dynamics between CAR T cells and target cells captures features that determine killing profiles

Suriya Selvarajan, Kevin L. Scrudders, Kenneth Rodriguez-Lopez, Suilan Zheng, Bo Huang, Philip Stewart Low, Raghu Pasupathy, Shalini T. Low-Nam

The paper develops a mechanistic model to predict CAR T cell killing of tumor cells based on contact dynamics and extracts parameters that determine killing efficiency and tumor resilience.

bioRxiv · Jun 24, 2025 · PreprintBiophysics