Author

Suriya Selvarajan

Purdue University West LafayettePrimary ORCID profile (0000-0002-1226-2935 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Suriya SelvarajaniD1 paper · Tata Institute of Fundamental Research

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Kevin L. ScruddersiD· 3 shared Shalini T. Low-NamiD· 3 shared Kenneth Rodriguez-Lopez· 2 shared Philip Stewart LowiD· 2 shared Suilan ZhengiD· 2 shared Alex J Alonzo· 1 shared Andrew Walke· 1 shared Ankona DattaiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

Kevin L. ScruddersORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Direct measurement of PIP2 densities in biological membranes using a peptide-based sensor

Vinay K. Menon, Joy Wu, Alex J Alonzo, Kevin L. Scrudders, Kaitlyn A. Rogers, Suriya Selvarajan, Andrew Walke, Jennifer Pellicier-Caraballo, Rajasree Kundu, Samsuzzoha Mondal, Ankona Datta, Shalini T. Low-Nam

The paper develops a peptide-based sensor to measure PI(4,5)P2 densities in membranes, showing mutation-specific changes in surface levels in cells with Ras mutations.

Journal of Biological Chemistry · Oct 16, 2025Peer-reviewedBiochemistry

CAR T cell cytotoxic responses are rapidly generated and sensitive to the unligated TCR

Kevin L. Scrudders, Suriya Selvarajan, Kenneth Rodriguez-Lopez, Weichuan Luo, Bo Huang, Suilan Zheng, Geoffrey H. Graff, Francisco N. Barrera, Philip Stewart Low, Shalini T. Low-Nam

This study investigates CAR T cell cytotoxic responses, showing they are sensitive to TCR interactions and can be modulated by inhibitory peptides.

bioRxiv · Jul 25, 2025 · PreprintImmunology

A mechanistic model for dynamics between CAR T cells and target cells captures features that determine killing profiles

Suriya Selvarajan, Kevin L. Scrudders, Kenneth Rodriguez-Lopez, Suilan Zheng, Bo Huang, Philip Stewart Low, Raghu Pasupathy, Shalini T. Low-Nam

The paper develops a mechanistic model to predict CAR T cell killing of tumor cells based on contact dynamics and extracts parameters that determine killing efficiency and tumor resilience.

bioRxiv · Jun 24, 2025 · PreprintBiophysics