A massively parallel synthetic gene atlas for learning compact cis-regulatory grammar across cellular contexts
Timo Hagen, Isabelle Liu, Ariana A. Nagainis, Noosha Khosrojerdi, Hassan Yousefi, Tess Gunnels, Amir H. Moarefi, Kevin Green, Nazli Azimi, Amir Momen-Roknabadi, Kevin R. Kipp, Hani Goodarzi
The paper introduces a synthetic gene atlas to study cis-regulatory elements across cell lines, enabling virtual-cell modeling by expanding gene regulatory networks with defined regulatory codes.
bioRxiv · Sep 14, 2026 · PreprintSystems Biology