Author

Klaus Dinkel

Lead Discovery Center (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jaideep KesavaniD· 2 shared Michael Hamacher· 2 shared Tobías EngeliD· 2 shared Alan BeausangiD· 1 shared Ana Fernandez Martin· 1 shared Anne Marie O'CallaghaniD· 1 shared Austin Lacey· 1 shared Beatriz Gil· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Jaideep KesavanORCID

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2 papers

Recent·Most cited

P2X7 receptor antagonism potentiates seizure-suppressive effects of anti-seizure medications in human resected epileptic brain tissue

Ana Fernandez Martin, Beatriz Gil, Meghma Mitra, Jaideep Kesavan, Austin Lacey, Meng-Juan Sun, Anne Marie O'Callaghan, Vincent Healy, Norman Delanty, Alan Beausang, Francesca M. Brett, Michael A. Farrell, Jane Cryan, Donncha F. O’Brien, Kieron J. Sweeney, , Tobías Engel

This study shows that P2X7R antagonists enhance the effectiveness of anti-seizure medications in human epileptic brain tissue by reducing inflammation and improving drug response.

bioRxiv · Sep 24, 2026 · PreprintNeuroscience

Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived neurons and astrocytes

Jaideep Kesavan, Orla Watters, Klaus Dinkel, Michael Hamacher, Jochen H.M. Prehn, David Clifford Henshall, Tobías Engel

This study demonstrates functional P2X7R expression in human iPSC-derived neurons and astrocytes using calcium imaging and immunostaining.

bioRxiv · Mar 28, 2021 · PreprintNeuroscience