Author

Kristen Castillo

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Brigitte N. GompertsiD· 3 shared Chandani SeniD· 3 shared Tammy M. RickabaughiD· 3 shared Justin LangermaniD· 2 shared Kathrin PlathiD· 2 shared Rachana R. ChandraniD· 2 shared WooSuk Choi· 2 shared Abdo DurraiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Brigitte N. GompertsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis

Chandani Sen, Justin Langerman, Konstantinos–Dionysios Alysandratos, Andrea Brigitta Alber, Caroline L. Cherry, Kristen Castillo, Sarah Siegel, Rachana R. Chandran, WooSuk Choi, Tammy M. Rickabaugh, Darrell N. Kotton, Kathrin Plath, Brigitte N. Gomperts

This study develops a 3D co-culture organoid model of IPF to investigate epithelial-fibroblast interactions and test anti-fibrotic drugs.

bioRxiv · Jun 25, 2026 · PreprintCell Biology

High Throughput Screening with a Primary Human Mucociliary Airway Model Identifies a Small Molecule with Anti-SARS-CoV-2 Activity

Chandani Sen, Tammy M. Rickabaugh, Arjit Vijey Jeyachandran, Constance Yuen, Maisam Ghannam, Abdo Durra, Adam W. Aziz, Kristen Castillo, Gustavo Garcia, Arunima Purkayastha, Brandon Han, Felix W. Boulton, Eugene L. Piatnitski Chekler, Robert G. Garces, Karen C. Wolff, , Brigitte N. Gomperts

This study uses a primary human stem cell-based airway model to screen 2100 compounds and identifies a small molecule effective against SARS-CoV-2 and its Omicron variant.

Respiratory Research · Jan 16, 2025Peer-reviewedCell Biology

Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis

Rachana R. Chandran, Preethi Vijayaraj, Rolando García-Milian, Jade King, Kristen Castillo, Liang Chen, Yu Mi Kwon, Sarai William, Tammy M. Rickabaugh, Justin Langerman, Woosuk Choi, Chandani Sen, Jacelyn E. Peabody Lever, Qian Li, Nikoleta Pavelková, , Brigitte N. Gomperts

The study identifies loss of cell junctions and matrix dysregulation as drivers of epithelial desquamation and fibrosis in IPF distal bronchioles.

bioRxiv · Jun 17, 2024 · PreprintPathology