Rolando García-Milian

This study identifies SPINK1 as a regulator of epigenomic states and stemness in PDAC through its interaction with COL18A1 and endostatin release.

EnrichViz provides an interactive R Shiny tool for visualizing pathway enrichment results from omics data without requiring coding.

This paper shows that renalase activates mitochondrial leak metabolism to enhance protein synthesis and protect cells from stress and injury.

The paper investigates how proliferative arrest affects neuron differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease (CJ) infected rat septal neurons, identifying key transcriptomic changes and immune responses.

This paper identifies RAB1A and ARFGAP1-positive membranes as essential for autophagosome biogenesis, interacting with ATG2A to support lipid transport during autophagosome formation.

The study identifies loss of cell junctions and matrix dysregulation as drivers of epithelial desquamation and fibrosis in IPF distal bronchioles.

The paper uses single-cell RNA sequencing to show cyclophosphamide induces apoptosis in human ovarian primordial follicles, not follicle growth activation, causing acute ovarian reserve depletion.