Author

Kyle A. van Allen

Carleton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Jennifer E. BruiniD· 2 shared Antonio A. HansoniD· 1 shared Austin Bautista· 1 shared Carole Lyn YaukiD· 1 shared Erin E. MulvihilliD· 1 shared Erin J. VanzyliD· 1 shared Evgenia Fadzeyeva· 1 shared Francis C. LynniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Jennifer E. BruinORCID

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2 papers

Recent·Most cited

Cisplatin exposure dysregulates pancreatic islet function in male mice

Lahari Basu, Lili Grieco-St-Pierre, Ma. Enrica Angela Ching, John D. H. Stead, Antonio A. Hanson, Jana Palaniyandi, Erin J. Vanzyl, Myriam P Hoyeck, Kelsea S. McKay, Kyle A. van Allen, Hyojin Lee, Xiao-Qing Dai, Austin Bautista, Evgenia Fadzeyeva, Erin E. Mulvihill, , Jennifer E. Bruin

This study shows cisplatin exposure impairs pancreatic islet function in male mice by disrupting insulin secretion and causing DNA damage in beta cells.

Diabetes · Jan 14, 2025Peer-reviewedMolecular Biology

Crosstalk between the aryl hydrocarbon receptor and hypoxia inducible factor 1α pathways impairs downstream dioxin response in human islet models

Noa Gang, Kyle A. van Allen, William Glen Willmore, Francis C. Lynn, Jennifer E. Bruin

This study investigates AHR-HIF1 pathway crosstalk in islet cells and finds hypoxia suppresses CYP1A1 and G6PC2 expression, with HIF1 dominating over AHR during TCDD + hypoxia co-treatment.

bioRxiv · Sep 25, 2024 · PreprintMolecular Biology