Author

L. A. O'Neill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

D. G. Ryan· 2 shared A. Casey· 1 shared A. I. Lamond· 1 shared A. J. Brenes· 1 shared A. L. Gorman· 1 shared A. P. Bracken· 1 shared A. T. Dinkova-Kostova· 1 shared A. Y. Abramov· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

D. G. Ryan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivOct 12, 2021

Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses

M. L. Lundahl, M. Mitermite, D. G. Ryan…·E. C. Lavelle

This study shows that IL-4 and IL-13 activation of macrophages induces protective innate memory against mycobacterial infection through enhanced OXPHOS-driven pro-inflammatory responses.

DOI 10.7554/elife.74690

humanmouse

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 13, 2021

Nrf2 is a central regulator of the metabolic landscape in macrophages and finetunes their inflammatory response

D. G. Ryan, E. V. Knatko, A. Casey…·A. T. Dinkova-Kostova

This study shows Nrf2 regulates macrophage metabolism, redox balance, and inflammatory responses, with 4-OI modulating these effects through Nrf2.

DOI 10.1101/2021.08.13.456204

mouseproteomics

𝕏 PostBluesky