Author

A. J. Brenes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Assay:proteomics· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. I. Lamond· 2 shared D. A. Cantrell· 2 shared J. L. Hukelmann· 2 shared L. Spinelli· 2 shared M. Swamy· 2 shared O. J. James· 2 shared A. Casey· 1 shared A. I. I. Lamond· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. I. Lamond

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Optimising Spectronaut search parameters to improve data quality with minimal proteome coverage reductions in DIA analyses of heterogeneous samples

C. P. Baker, R. Bruderer, J. C. Abbott, S. Arthur, A. J. Brenes

The paper optimizes Spectronaut search parameters to reduce false positives in DIA proteomics with minimal loss of true positives in heterogeneous samples.

bioRxiv · Oct 11, 2023 · PreprintBiochemistry

Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures

G. Sollberger, A. J. Brenes, J. Warner, J. S. C. Arthur, A. J. Howden

The paper uses quantitative proteomics to identify tissue-specific, infection-induced, and species-specific neutrophil protein signatures in mice and humans.

bioRxiv · Sep 5, 2023 · PreprintImmunology

The Immunological Proteome Resource

A. J. Brenes, J. L. Hukelmann, L. Spinelli, A. J. M. Howden, J. M. Marchingo, L. V. Sinclair, C. Rollings, O. J. James, I. R. Phair, S. P. Matthews, S. H. Ross, S. C. Arthur, M. Swamy, D. K. Finlay, A. I. I. Lamond, D. A. Cantrell

The paper introduces ImmPRes, a proteomic resource integrating mass-spectrometry data from murine hematopoietic cells to study immune activation and signaling.

bioRxiv · Aug 29, 2022Immunology

Nrf2 is a central regulator of the metabolic landscape in macrophages and finetunes their inflammatory response

D. G. Ryan, E. V. Knatko, A. Casey, J. L. Hukelmann, A. J. Brenes, S. Dayalan Naidu, M. Higgins, L. Tronci, E. Nikitopoulou, L. A. O'Neill, A. I. Lamond, A. Y. Abramov, D. A. Cantrell, M. P. Murphy, A. T. Dinkova-Kostova

This study shows Nrf2 regulates macrophage metabolism, redox balance, and inflammatory responses, with 4-OI modulating these effects through Nrf2.

bioRxiv · Aug 13, 2021 · PreprintImmunology

Tissue environment, not ontogeny, defines intestinal intraepithelial T lymphocytes

A. J. Brenes, M. Vandereyken, O. J. James, J. Hukelmann, L. Spinelli, A. I. Lamond, M. Swamy

The paper uses proteomic analysis to show that the gut environment, not developmental origin, shapes the functional properties of intestinal intraepithelial T lymphocytes.

bioRxiv · Mar 15, 2021Immunology