Author

L. Brautigam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Hagenkort· 1 shared A. Stolz· 1 shared A.-S. Jemth· 1 shared A.-S. Oppelt· 1 shared C. E. Strom· 1 shared C. Gokturk· 1 shared C. Kalderen· 1 shared E. Homan· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Hagenkort

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.

N. F. H. N. van Bree, A.-S. Oppelt, S. Lindstrom, L. Zhou, L. Boutin, J. I. Johnsen, L. Brautigam, M. T. Wilhelm

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.

bioRxiv · Feb 21, 2024Cancer Biology

MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells

H. Gad, O. Mortusewicz, S. G. Rudd, A. Stolz, N. Amaral, L. Brautigam, L. Pudelko, K. Sanjiv, C. Kalderen, A.-S. Jemth, I. Almlof, T. Visnes, N. Schultz, J. Bostrom, J. M. Calderon Montano, , T. Helleday

This study identifies MTH1's role in mitosis and shows that potent MTH1 inhibitors cause mitotic arrest by disrupting tubulin polymerization and suppressing ROS.

bioRxiv · Sep 5, 2019 · PreprintCancer Biology