Author

L. Chalklen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metagenomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

L. J. Hall· 3 shared C. Alcon-Giner· 2 shared M. Kujawska· 2 shared S. Caim· 2 shared A. J. Watson· 1 shared A. Shaw· 1 shared A. Wijeyesekera· 1 shared C. Leclaire· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

L. J. Hall

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3 papers

Recent·Most cited

Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome

C. Alcon-Giner, M. Dalby, S. Caim, J. Ketskemety, A. Shaw, K. Sim, M. Lawson, R. Kiu, C. Leclaire, L. Chalklen, M. Kujawska, S. Mitra, F. Fardus-Reid, G. Belteki, K. Lloyd, , L. J. Hall

This study shows that supplementing preterm infants with Bifidobacterium and Lactobacillus changes their gut microbiota and increases fecal acetate and lactate levels, resembling a full-term infant's gut environment.

bioRxiv · Oct 4, 2019Microbiology

The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding

K. R. Hughes, Z. Schofield, M. J. Dalby, S. Caim, L. Chalklen, F. Bernuzzi, C. Alcon-Giner, G. Le Gall, A. J. Watson, L. J. Hall

This study shows that early life gut microbiota in mice prevents pathological small intestinal epithelial cell shedding, with antibiotic treatment reversing this protection.

bioRxiv · Oct 2, 2019Microbiology

Infant diet promotes Bifidobacterium community cooperation within a single ecosystem

M. A. Lawson, I. J. O'Neill, M. Kujawska, A. Wijeyesekera, Z. Flegg, L. Chalklen, L. J. Hall

The paper investigates how infant diet influences bifidobacterial community composition and cooperation in the gut, showing resource sharing enhances nutrient utilization and supports Bifidobacterium dominance.

bioRxiv · Jul 23, 2019Microbiology