Author

R. Kiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:differential expression· 3 Assay:metagenomics· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

L. J. Hall· 9 shared S. Caim· 5 shared C. Alcon-Giner· 3 shared C. Leclaire· 3 shared D. Pickard· 3 shared G. Dougan· 3 shared M. Kujawska· 3 shared P. Clarke· 3 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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9 shared papersMicrobiology

L. J. Hall

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Gut microbiota and faecal cytokine profiles of rural Cambodian infants and links to early life nutrition and diarrhoeal episodes.

M. J. Dalby, R. Kiu, I. R. Serghiou, A. Miyazaki, H. Acford-Palmer, R. Tung, S. Caim, S. Phillips, M. Kujawska, M. Matsui, A. Iwamoto, B. Taking, S. E. Cox, L. J. Hall

This study examines gut microbiota and cytokine profiles in rural Cambodian infants, finding associations between breastfeeding, pathogen exposure, and microbial composition.

bioRxiv · Jul 24, 2023 · PreprintMicrobiology

Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice

J. Lopez-Tello, Z. Schofield, R. Kiu, M. J. Dalby, D. van Sinderen, G. Le Gall, A. N. Sferruzzi-Perri, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 in the maternal gut microbiota promotes placental development, nutrient transport, and fetal growth in mice.

Cellular and Molecular Life Sciences · Jun 28, 2022Peer-reviewedPhysiology

A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity

S. G. Javvadi, M. Kujawska, D. Papp, A. M. Gontarczyk, A. Jordan, M. A. Lawson, I. J. O'Neill, C. Alcon-Giner, R. Kiu, P. Clarke, N. Beraza, L. J. Hall

bioRxiv · Jan 27, 2022 · PreprintMicrobiology

Dissemination and pathogenesis of toxigenic Clostridium perfringens strains linked to neonatal intensive care units and Necrotising Enterocolitis

R. Kiu, A. Shaw, K. Sim, H. Bedwell, E. Cornwell, D. Pickard, G. Belteki, J. Malsom, S. Philips, G. Young, Z. Schofield, C. Alcon-Giner, J. Berrington, C. Stewart, G. Dougan, , L. J. Hall

This study identifies hypervirulent C. perfringens strains linked to NEC in preterm infants, showing their dissemination between hospitals and increased virulence.

bioRxiv · Aug 3, 2021 · PreprintMicrobiology

Clostridium perfringenosum sp. nov., a closely related species toClostridium perfringens and its virulence factors, isolated from a humansoft tissue infection

C. Rodriguez, R. Kiu, C. Quesada-Gomez, C. Sandi, L. J. Hall

This paper describes the discovery of a new Clostridium species, C. perfringenosum, closely related to C. perfringens, based on genomic and phenotypic analyses of isolates from a human infection.

bioRxiv · Dec 1, 2020 · PreprintMicrobiology

Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells

R. Kiu, A. Treveil, L. C. Harnisch, S. Caim, C. Leclaire, D. van Sinderen, T. Korcsmaros, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 significantly alters the transcriptome of neonatal intestinal epithelial cells, enhancing cell replication, differentiation, and growth.

bioRxiv · Mar 27, 2020Immunology

Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome

C. Alcon-Giner, M. Dalby, S. Caim, J. Ketskemety, A. Shaw, K. Sim, M. Lawson, R. Kiu, C. Leclaire, L. Chalklen, M. Kujawska, S. Mitra, F. Fardus-Reid, G. Belteki, K. Lloyd, , L. J. Hall

This study shows that supplementing preterm infants with Bifidobacterium and Lactobacillus changes their gut microbiota and increases fecal acetate and lactate levels, resembling a full-term infant's gut environment.

bioRxiv · Oct 4, 2019Microbiology

Genomic analysis on broiler-associated Clostridium perfringens strains and caecal microbiome profiling reveals key factors linked to poultry Necrotic Enteritis

R. Kiu, J. Brown, H. Bedwell, C. Leclaire, S. Caim, D. Pickard, G. Dougan, R. Dixon, L. J. Hall

This study identifies hypervirulent Clostridium perfringens strains and microbiome changes associated with necrotic enteritis in broiler chickens.

bioRxiv · Jul 9, 2019Microbiology

Phylogenomic analysis of Clostridium perfringens identifies isogenic strains in gastroenteritis outbreaks, and novel virulence-related features

R. Kiu, S. Caim, D. Pickard, A. Painset, C. Swift, G. Dougan, A. E. Mather, C. Amar, L. J. Hall

This study uses whole genome sequencing to analyze C. perfringens strains from gastroenteritis outbreaks, identifying isogenic strains and novel virulence features.

bioRxiv · Jun 13, 2019Microbiology