Author

C. Leclaire

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1

Frequent Co-Authors

L. J. Hall· 5 shared S. Caim· 5 shared C. Alcon-Giner· 3 shared M. Dalby· 3 shared R. Kiu· 3 shared A. Andrusaite· 2 shared G. Le Gall· 2 shared S. D. Robinson· 2 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCancer Biology

L. J. Hall

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells

R. Kiu, A. Treveil, L. C. Harnisch, S. Caim, C. Leclaire, D. van Sinderen, T. Korcsmaros, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 significantly alters the transcriptome of neonatal intestinal epithelial cells, enhancing cell replication, differentiation, and growth.

bioRxiv · Mar 27, 2020Immunology

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth via a mast cell-dependent pathway

B. M. Kirkup, A. M. McKee, M. Madgwick, C. A. Price, S. A. Dreger, K. A. Makin, S. Caim, G. Le Gall, J. Pavely, C. Leclaire, M. Dalby, C. Alcon-Giner, A. Andrusaite, M. Di Modica, T. Triulzi, , S. D. Robinson

This study shows antibiotic-induced gut microbiota disturbances accelerate breast tumour growth in mice via mast cell-dependent mechanisms.

bioRxiv · Mar 7, 2020 · PreprintCancer Biology

Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome

C. Alcon-Giner, M. Dalby, S. Caim, J. Ketskemety, A. Shaw, K. Sim, M. Lawson, R. Kiu, C. Leclaire, L. Chalklen, M. Kujawska, S. Mitra, F. Fardus-Reid, G. Belteki, K. Lloyd, , L. J. Hall

This study shows that supplementing preterm infants with Bifidobacterium and Lactobacillus changes their gut microbiota and increases fecal acetate and lactate levels, resembling a full-term infant's gut environment.

bioRxiv · Oct 4, 2019Microbiology

Genomic analysis on broiler-associated Clostridium perfringens strains and caecal microbiome profiling reveals key factors linked to poultry Necrotic Enteritis

R. Kiu, J. Brown, H. Bedwell, C. Leclaire, S. Caim, D. Pickard, G. Dougan, R. Dixon, L. J. Hall

This study identifies hypervirulent Clostridium perfringens strains and microbiome changes associated with necrotic enteritis in broiler chickens.

bioRxiv · Jul 9, 2019Microbiology

Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

B. Kirkup, A. McKee, K. Makin, J. Paveley, S. Caim, C. Alcon-Giner, C. Leclaire, M. Dalby, G. Le Gall, A. Andrusaite, P. Kreuzaler, P. Driscoll, J. MacRae, E. Calvani, A. Ghanate, , S. D. Robinson

This study shows that antibiotics disrupt the gut microbiota, leading to faster breast tumour growth and metabolic changes in mice.

bioRxiv · Feb 19, 2019 · PreprintCancer Biology