Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins
M. M. A. Rahim, B. Parsons, E. L. Price, P. D. Slaine, B. L. Chilvers, G. S. Seaton, A. Wight, S. Dey, S. L. Grandy, L. E. Anderson, N. Zamorano Cuervo, N. Grandvaux, M. M. Gaglia, A. A. Kelvin, D. A. Khaperskyy, , A. P. Makrigiannis
This paper shows that defective influenza A virus RNAs trigger MAVS-dependent upregulation of HLA class I proteins, which may aid viral evasion of innate immunity.
Journal of Virology · Jun 16, 2020Peer-reviewedMicrobiology