Author

L. F. Sobala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. J. Thompson· 1 shared D. S. Alonzi· 1 shared G. J. Davies· 1 shared J. D. Howe· 1 shared M. Hill· 1 shared N. Zitzmann· 1 shared P. Z. Fernandes· 1 shared S. Davies· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. J. Thompson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Evolution and phylogenetic distribution of endo-α-mannosidase

L. F. Sobala

This study investigates the evolutionary history of endo-α-mannosidase across eukaryotic clades, revealing its broader distribution and co-evolution with complex multicellularity.

bioRxiv · Dec 21, 2022Evolutionary Biology

Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

L. F. Sobala, P. Z. Fernandes, Z. Hakki, A. J. Thompson, J. D. Howe, M. Hill, N. Zitzmann, S. Davies, Z. Stamataki, T. D. Butters, D. S. Alonzi, S. J. Williams, G. J. Davies

The paper reports the structure of human MANEA and inhibitor complexes, revealing its mechanism and informing the development of antiviral agents against bovine viral diarrhea and dengue viruses.

bioRxiv · Jun 30, 2020Biochemistry