Author

W. Jacot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Mallavialle· 2 shared B. Orsetti· 2 shared C. Sardet· 2 shared C. Theillet· 2 shared L. B. Alcaraz· 2 shared P. Roger· 2 shared S. Du Manoir· 2 shared S. Guiu· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Mallavialle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Replication poison treated BRCA1-deficient breast cancers are prone to MRE11 over-resection resulting in single strand DNA accumulation and mitotic catastrophe

I. Tabet, E. Orhan, E. Candiello, L. Fenou, C. Velazquez, B. Orsetti, G. Rodier, W. Jacot, C. Ribeyre, C. Sardet, C. Theillet

This study shows BRCA1-deficient breast cancers are highly sensitive to gemcitabine, leading to ssDNA accumulation and mitotic catastrophe, which may enhance antitumor immune response.

bioRxiv · Oct 31, 2023 · PreprintCancer Biology

SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity

L. B. Alcaraz, A. Mallavialle, C. Mollevi, F. Boissiere Michot, H. Mansouri, J. Simony Lafontaine, V. Laurent Matha, T. Chardes, W. Jacot, A. Turtoi, P. Roger, S. Guiu, E. Liaudet Coopman

bioRxiv · Nov 3, 2021Cancer Biology

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

L. B. Alcaraz, A. Mallavialle, T. David, D. Derocq, F. Delolme, C. Dieryckx, F. Boissiere-Michot, J. Simony-Lafontaine, S. Du Manoir, P. Huesgen, C. M. Overall, S. Tartare-Deckert, W. Jacot, T. Chardes, S. Guiu, , E. Liaudet-Coopman

The paper identifies a 9-kDa SPARC fragment released by cathepsin D in TNBC that promotes tumor progression by enhancing cell migration and invasion.

bioRxiv · Oct 22, 2020 · PreprintCancer Biology

Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells

C. Fonti, A. Saumet, A. Abi-Khalil, B. Orsetti, W. Jacot, E. Cleroux, A. Bender, M. Dumas, E. Schmitt, J. Colinge, M. Weber, C. Sardet, S. du Manoir, C. Theillet

This study shows that activating different oncogenes in human mammary epithelial cells leads to distinct genetic and epigenetic changes, suggesting oncogene activation shapes breast cancer subtypes.

International Journal of Cancer · Jun 10, 2019Peer-reviewedCancer Biology