Author

L. Frezal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 2

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Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Organism:C. elegans· 3 Research Focus:host-pathogen & immune response· 3 Assay:DNA methylation· 2 Organism:bacteria (other)· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M.-A. Felix· 3 shared A. de Cara· 1 shared A. Fontanet· 1 shared A. Richaud· 1 shared A. Whibley· 1 shared C. Braendle· 1 shared C. Gilbert· 1 shared C. Ruckly· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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3 shared papersEvolutionary Biology

M.-A. Felix

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6 papers

Recent·Most cited

Genome-wide association and environmental suppression of the mortal germline phenotype of wild C. elegans

L. Frezal, M. Saglio, G. Zhang, L. Noble, A. Richaud, M.-A. Felix

This study identifies a genetic basis for a mortal germline phenotype in wild C. elegans and shows that environmental factors and non-genetic memory can suppress it.

bioRxiv · May 17, 2023 · PreprintEvolutionary Biology

Rapid emergence of extensively drug-resistant Shigella sonnei in France

S. Lefevre, E. Njamkepo, S. Feldman, C. Ruckly, I. Carle, M. Lejay-Collin, L. Fabre, I. Yassine, L. Frezal, M. Pardos de la Gandara, A. Fontanet, F.-X. Weill

The paper tracks the rise of extensively drug-resistant Shigella sonnei in France, identifying genetic clusters and resistance mechanisms in isolates from 2005 to 2021.

bioRxiv · Sep 7, 2022Microbiology

Noda-like RNA viruses infecting Caenorhabditis nematodes: sympatry, diversity and reassortment

L. Frezal, H. Jung, S. Tahan, D. Wang, M.-A. Felix

The paper identifies a new RNA virus infecting Caenorhabditis nematodes, describes co-infections and reassortment patterns, and shows host-virus genotype interactions affecting competition.

bioRxiv · Apr 12, 2019Microbiology

Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes

D. Lee, S. Zdraljevic, D. E. Cook, L. Frezal, J.-C. Hsu, M. G. Sterken, J. A. G. Riksen, J. Wang, J. E. Kammenga, C. Braendle, M.-A. Felix, F. C. Schroeder, E. C. Andersen

The paper shows that copy-number variation of pheromone receptor genes in C. elegans is shaped by selection and gene flow, contributing to differences in pheromone responses across habitats.

bioRxiv · Mar 26, 2019 · PreprintEvolutionary Biology

Supergene evolution triggered by the introgression of a chromosomal inversion

P. Jay, A. Whibley, L. Frezal, A. de Cara, R. W. Nowell, J. Mallet, K. K. Dasmahapatra, M. Joron

The paper shows that supergene alleles in Heliconius numata butterflies arise from introgression of a chromosomal inversion, leading to balanced polymorphism and mimicry polymorphism.

bioRxiv · Dec 14, 2017Evolutionary Biology

Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements

S. H. Lewis, K. A. Quarles, Y. Yang, M. Tanguy, L. Frezal, S. A. Smith, P. P. Sharma, R. Cordaux, C. Gilbert, I. Giraud, D. H. Collins, P. D. Zamore, E. A. Miska, P. Sarkies, F. M. Jiggins

The paper analyzes piRNA pathways across 20 arthropod species, finding somatic piRNAs as an ancestral defense against transposable elements.

bioRxiv · Oct 4, 2017Evolutionary Biology