Author

M. Tanguy

Primary ORCID profile (0000-0003-4862-0981 · 8 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. TanguyiD8 papers · Beth Israel Deaconess Medical Center

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

E. A. Miska· 2 shared P. Sarkies· 2 shared A. Giess· 1 shared A. M. Flanagan· 1 shared A. Sosinky· 1 shared C. Gilbert· 1 shared D. H. Collins· 1 shared F. Amary· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersEvolutionary Biology

E. A. Miska

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Author profile →

3 papers

Recent·Most cited

Mechanisms underpinning osteosarcoma genome complexity and evolution

J. Espejo Valle-Inclan, S. De Noon, K. Trevers, H. Elrick, M. Tanguy, T. Butters, F. Muyas, F. Amary, R. Tirabosco, A. Giess, A. Sosinky, G. Elgar, A. M. Flanagan, I. Cortes-Ciriano

This study identifies chromothripsis and a novel LTA chromothripsis mechanism driving genome complexity and evolution in osteosarcoma, with prognostic implications for high-grade tumors.

bioRxiv · Dec 29, 2023 · PreprintCancer Biology

Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements

S. H. Lewis, K. A. Quarles, Y. Yang, M. Tanguy, L. Frezal, S. A. Smith, P. P. Sharma, R. Cordaux, C. Gilbert, I. Giraud, D. H. Collins, P. D. Zamore, E. A. Miska, P. Sarkies, F. M. Jiggins

The paper analyzes piRNA pathways across 20 arthropod species, finding somatic piRNAs as an ancestral defense against transposable elements.

bioRxiv · Oct 4, 2017Evolutionary Biology

An alternative STAT signaling pathway acts in antiviral immunity in Caenorhabditis elegans

M. Tanguy, L. Veron, P. Stempor, J. Ahringer, P. Sarkies, E. A. Miska

The paper identifies a novel STAT signaling pathway in C. elegans that suppresses antiviral immunity, contrasting with the mammalian interferon system.

bioRxiv · Feb 25, 2017Immunology