Author

L. H. Vandenberghe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. Sanmiguel· 2 shared N. Zabaleta· 2 shared A. Cucalon· 1 shared A. G. Schmidt· 1 shared A. Griffiths· 1 shared A. Honko· 1 shared A. Ryan· 1 shared A. Sheridan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

J. Sanmiguel

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2 papers

Recent·Most cited

Correlating physicochemical and biological properties to define critical quality attributes of a recombinant AAV vaccine candidate

P. Kumar, M. Wang, O. S. Kumru, J. Hickey, J. Sanmiguel, N. Zabaleta, L. H. Vandenberghe, S. B. Joshi, D. B. Volkin

The paper correlates physicochemical properties of an rAAV vaccine candidate with its biological potency, showing links between physical stability, transduction efficiency, and immunogenicity.

bioRxiv · Mar 10, 2023Immunology

Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates

N. Zabaleta, W. Dai, U. Bhatt, J. A. Chichester, J. Sanmiguel, R. Estelien, K. T. Michalson, C. Diop, D. Maciorowski, W. Qi, E. Hudspeth, A. Cucalon, C. D. Dyer, M. B. Pampena, J. J. Knox, , L. H. Vandenberghe

This paper evaluates an AAV-based COVID-19 vaccine in mice and non-human primates, showing sustained neutralizing antibodies and memory T-cells, with room-temperature stability and scalable production.

bioRxiv · Jan 5, 2021 · PreprintImmunology