Author

N. Zabaleta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. Sanmiguel· 2 shared L. H. Vandenberghe· 2 shared A. Cucalon· 1 shared A. G. Schmidt· 1 shared A. Garcia-Torralba· 1 shared A. Griffiths· 1 shared A. Honko· 1 shared A. Ryan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

J. Sanmiguel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Correlating physicochemical and biological properties to define critical quality attributes of a recombinant AAV vaccine candidate

P. Kumar, M. Wang, O. S. Kumru, J. Hickey, J. Sanmiguel, N. Zabaleta, L. H. Vandenberghe, S. B. Joshi, D. B. Volkin

The paper correlates physicochemical properties of an rAAV vaccine candidate with its biological potency, showing links between physical stability, transduction efficiency, and immunogenicity.

bioRxiv · Mar 10, 2023Immunology

Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates

N. Zabaleta, W. Dai, U. Bhatt, J. A. Chichester, J. Sanmiguel, R. Estelien, K. T. Michalson, C. Diop, D. Maciorowski, W. Qi, E. Hudspeth, A. Cucalon, C. D. Dyer, M. B. Pampena, J. J. Knox, , L. H. Vandenberghe

This paper evaluates an AAV-based COVID-19 vaccine in mice and non-human primates, showing sustained neutralizing antibodies and memory T-cells, with room-temperature stability and scalable production.

bioRxiv · Jan 5, 2021 · PreprintImmunology

In vitro and In vivo Genetic Disease Modelling via NHEJ precise deletions using CRISPR/Cas9

S. Lopez-Manzaneda, I. Ojeda-Perez, N. Zabaleta, A. Garcia-Torralba, O. Alberquilla, R. Torres, R. Sanchez-Dominguez, L. Torella, E. Olivier, J. Mountford, J. C. Ramirez, J. A. Bueren, G. Gonzalez-Aseguinolaza, J. C. Segovia

The paper demonstrates that using two guideRNAs at optimal distance and orientation with CRISPR/Cas9 enables precise deletions for creating genetically reproducible disease models in human and mouse cells.

bioRxiv · Mar 25, 2020Bioengineering