Author

L. Kaderali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Zitzmann· 2 shared M. Binder· 2 shared R. Bartenschlager· 2 shared A. Mueller· 1 shared A. Pichlmair· 1 shared A. Piras· 1 shared A. S. Perelson· 1 shared B. Bruegger· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Zitzmann

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

S. S. Burkart, D. Schweinoch, J. Frankish, C. Sparn, S. Wuest, C. Urban, A. Piras, A. Pichlmair, J. Willemsen, L. Kaderali, M. Binder

This study characterizes the kinetics of RIG-I signaling and develops a dynamic model to predict antiviral responses and virus-host interactions.

bioRxiv · Aug 5, 2022Immunology

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

C. Zitzmann, C. Dächert, B. Schmid, H. van der Schaar, M. van Hemert, A. S. Perelson, F. van Kuppeveld, R. Bartenschlager, M. Binder, L. Kaderali

This paper develops a mathematical model of plus-strand RNA virus replication for HCV, DENV, and CVB3, identifying viral RNA translation and polyprotein cleavage as key targets for broad-spectrum antiviral strategies.

bioRxiv · Jul 25, 2022Microbiology

Convergent use of phosphatidic acid for Hepatitis C virus and SARS-CoV-2 replication organelle formation

K. Tabata, V. Prasad, D. Paul, J.-Y. Lee, M.-T. Pham, W.-I. Twu, C. J. Neufeldt, M. Cortese, B. Cerikan, C. S. Tran, C. Luechtenborg, P. Vkovski, K. Hoermann, A. Mueller, C. Zitzmann, , R. Bartenschlager

This study identifies phosphatidic acid as critical for double membrane vesicle formation in HCV and SARS-CoV-2 replication, suggesting host-targeted PA synthesis inhibition as a therapeutic strategy.

bioRxiv · May 10, 2021Microbiology