Author

A. Piras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Pichlmair· 4 shared C. Urban· 2 shared M. Binder· 2 shared A. Betz· 1 shared A. Binz· 1 shared A. Grünewald· 1 shared A. Hickford Martinez· 1 shared A. K. de Regt· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

A. Pichlmair

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RBM39 shapes innate immunity through transcriptional and splicing control of key factors of the interferon response

T.-F. Li, P. Rothhaar, A. Lang, O. Gruenvogel, O. Colasanti, S. M. Olivera Ugarte, J. Traut, A. Piras, N. Acosta-Rivero, V. Goncalves Magalhaes, E. Springer, A. Betz, H.-E. Huang, J. Park, R. Qiu, , V. Lohmann

This study identifies RBM39 as a regulator of innate immunity by controlling transcription and splicing of key interferon response factors, revealing its potential as a therapeutic target.

bioRxiv · Oct 13, 2023 · PreprintImmunology

hnRNPM and ELAVL1 control type I interferon induction by promoting IRF3 phosphorylation downstream of both cGAS and RIG-I

A. Kirchhoff, A.-M. Herzner, C. Urban, A. Piras, R. Düster, J. Wegner, A. Grünewald, T. M. Schlee-Guimaraes, K. Ciupka, P. Leka, R. J. Bootz, A. K. de Regt, B. Kümmerer, M. Honholt Christensen, F. I. Schmidt, , M. Schlee

bioRxiv · Jun 23, 2023 · PreprintImmunology

High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

S. S. Burkart, D. Schweinoch, J. Frankish, C. Sparn, S. Wuest, C. Urban, A. Piras, A. Pichlmair, J. Willemsen, L. Kaderali, M. Binder

This study characterizes the kinetics of RIG-I signaling and develops a dynamic model to predict antiviral responses and virus-host interactions.

bioRxiv · Aug 5, 2022Immunology

The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

B. Sodeik, M. C. Serrero, V. Girault, S. Weigang, T. M. Greco, A. Ramos Nascimento, F. Anderson, A. Piras, A. Hickford Martinez, J. Hertzog, A. Binz, A. Pohlmann, U. Prank, J. Rehwinkel, R. Bauerfeind, , G. Kochs

This study identifies MxB as an interferon-inducible GTPase that disassembles herpesvirus capsids, promoting genome release and enhancing innate immune responses.

bioRxiv · Jan 25, 2022Microbiology