Author

L. M. G. Pena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Marti· 3 shared E. D. Abel· 3 shared E. T. Weatherford· 3 shared R. O. Pereira· 3 shared S. H. Bjorkman· 3 shared C. M. Adams· 2 shared J. H. Chen· 2 shared J. Jena· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

A. Marti

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Author profile →

3 papers

Recent·Most cited

PhysiologybioRxivMar 9, 2023

ATF4 Expression in Thermogenic Adipocytes is Required for Cold-Induced Thermogenesis in Mice via FGF21-Independent Mechanisms

S. H. Bjorkman, A. Marti, J. Jena…·R. O. Pereira

This study shows ATF4 is essential for cold-induced thermogenesis in mice through amino acid metabolism, independent of FGF21, while FGF21 is not required for thermoregulation.

DOI 10.1038/s41598-024-52004-8

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivDec 23, 2022

GDF15 Is Required for Cold-Induced Thermogenesis and Contributes to Improve Systemic Metabolic Health Following Loss of OPA1 in Brown Adipocytes

J. Jena, L. M. G. Pena, E. T. Weatherford…·R. O. Pereira

This study identifies GDF15 as a mediator of improved metabolic health and thermogenesis in OPA1-deficient brown adipocytes, showing its role in glucose homeostasis and cold-induced thermogenesis.

DOI 10.7554/elife.86452

mousebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivJan 4, 2021

OPA1 Deletion in Brown Adipose Tissue Improves Thermoregulation and Systemic Metabolism via FGF21

R. O. Pereira, A. Marti, A. C. Olvera…·E. D. Abel

This study shows that deleting OPA1 in brown adipose tissue enhances thermoregulation and metabolism through the ATF4-FGF21 pathway, independent of thermogenesis.

DOI 10.7554/elife.66519

mousebulk RNA-seq

𝕏 PostBluesky