Author

L. Nitschke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

M. S. Macauley· 2 shared A. Alborzian Deh Sheikh· 1 shared A. E. Hauser· 1 shared A. Marki· 1 shared A. Rakhymzhan· 1 shared B. M. Arlian· 1 shared B. Ocon· 1 shared C. A. Lowell· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

M. S. Macauley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Coordinated changes in glycosylation regulate the germinal centre through CD22

J. R. Enterina, S. Sarkar, L. Streith, J. Jung, B. M. Arlian, S. J. Meyer, H. Takematsu, C. Xiao, T. Baldwin, L. Nitschke, M. J. Shlomchick, J. C. Paulson, M. S. Macauley

This study shows that glycan remodeling and CD22 downregulation are essential for proper germinal center function, including plasma cell output and antibody affinity maturation.

bioRxiv · Apr 30, 2021 · PreprintImmunology

Selective augmentation of intestinal immunity by CD22-dependent SHP-1 control of β7 integrin expression.

R. Ballet, C. Brandl, N. Feng, J. Berri, J. Cheng, B. Ocon, A. Alborzian Deh Sheikh, A. Marki, C. L. Abram, C. A. Lowell, T. Tsubata, H. B. Greenberg, M. S. Macauley, K. Ley, L. Nitschke, E. Butcher

This study identifies CD22-dependent SHP-1 regulation of β7 integrin expression, showing its role in intestinal immunity and pathogen clearance.

bioRxiv · Jan 31, 2020 · PreprintImmunology

Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages

C. Ulbricht, R. Leben, A. Rakhymzhan, F. Kirchhoff, L. Nitschke, H. Radbruch, R. A. Niesner, A. E. Hauser

The paper quantifies absolute cytoplasmic calcium in B cells using a novel reporter strain and intravital imaging, revealing dynamic calcium fluctuations during differentiation.

bioRxiv · Dec 13, 2019Immunology