Experimental evolution reveals post-transcriptional regulation as a novel driver of Leishmania fitness gain
L. Piel, K. S. Rajan, G. Bussotti, H. Varet, R. Legendre, C. Proux, T. Douche, Q. Giai Gianetto, T. Chaze, T. Cokelaer, B. Vojtkova, N. Gordon-Bar, T. Doniger, S. Cohen-Chalamish, P. Rengaraj, , G. F. Spaeth
This study shows that post-transcriptional regulation, not just genome instability, drives fitness gain in Leishmania parasites during in vitro adaptation.
bioRxiv · Mar 22, 2021 · PreprintMicrobiology