Author

C. Proux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

G. F. Spaeth· 4 shared H. Varet· 4 shared R. Legendre· 4 shared E. Prina· 3 shared H. Lecoeur· 3 shared P. Bousso· 2 shared S. Zhang· 2 shared A. Boland· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

G. F. Spaeth

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION

C. Gharsallah, H. Lecoeur, H. Varet, R. Legendre, O. Sismeiro, J.-Y. Coppee, C. Proux, E. Scarfiello, A. Bruckmann, G. Meister, E. Prina, G. F. Spaeth

bioRxiv · Mar 24, 2024 · PreprintMicrobiology

Leishmania amazonensis controls macrophage-regulated cell death to establish chronic infection in vitro and in vivo

H. Lecoeur, S. Zhang, H. Varet, R. Legendre, C. Proux, C. Granjean, P. Bousso, E. Prina, G. F. Spaeth

This study shows Leishmania amazonensis suppresses macrophage-regulated cell death pathways to promote chronic infection in vitro and in vivo.

bioRxiv · Sep 14, 2022 · PreprintMicrobiology

The m6A reader IGF2BP2 directs immune-metabolic reprogramming in Leishmania amazonensis-infected macrophages

S. Zhang, H. Lecoeur, H. Varet, R. Legendre, N. Mahtal, C. Proux, N. Aulner, S. Short, C. Grandjean, P. Bousso, E. Prina, G. F. Spaeth

This study identifies IGF2BP2 as an m6A reader that stabilizes glycolytic transcripts in Leishmania-infected macrophages, promoting HIF-1-independent glycolysis and immune-metabolic reprogramming.

bioRxiv · Sep 8, 2022 · PreprintImmunology

Differential transcriptomic response of Anopheles arabiensis to Plasmodium vivax and Plasmodium falciparum infection

M. Tchioffo Tsapi, E. Kornobis, N. Puchot, S. English, C. Proux, J. Goupeyou-Youmsi, A. Sakuntabhai, M.-A. Dillies, M. Randrianarivelojosia, R. Girod, M. o. Ndiath, C. Bourgouin

This study compares the molecular responses of Anopheles arabiensis to Plasmodium vivax and Plasmodium falciparum infections, identifying differentially expressed genes and long non-coding RNAs.

bioRxiv · May 28, 2021 · PreprintMicrobiology

Experimental evolution reveals post-transcriptional regulation as a novel driver of Leishmania fitness gain

L. Piel, K. S. Rajan, G. Bussotti, H. Varet, R. Legendre, C. Proux, T. Douche, Q. Giai Gianetto, T. Chaze, T. Cokelaer, B. Vojtkova, N. Gordon-Bar, T. Doniger, S. Cohen-Chalamish, P. Rengaraj, , G. F. Spaeth

This study shows that post-transcriptional regulation, not just genome instability, drives fitness gain in Leishmania parasites during in vitro adaptation.

bioRxiv · Mar 22, 2021 · PreprintMicrobiology