Author

L. Quan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

B. Duan· 1 shared C. Jin· 1 shared D. Centeno· 1 shared D. Kalyon· 1 shared D. Kung· 1 shared D. Seto· 1 shared E. Dziabaszewska· 1 shared E. Nowak-Markwitz· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

B. Duan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J. Ou, W. Lan, X. Wu, T. Zhao, B. Duan, P. Yang, Y. Ren, L. Quan, W. Zhao, D. Seto, J. Chodosh, J. Wu, Q. Zhang

This study identifies multiple recombination events between SARS-CoV-2 Omicron subvariants and other variants, suggesting co-infection and recombination drive viral evolution.

bioRxiv · Mar 13, 2022Microbiology

Extracellular Matrix Modulates Outgrowth Dynamics in Ovarian Cancer

S. Alshehri, T. Pavlovic, S. Farsinejad, P. Behboodi, L. Quan, D. Centeno, D. Kung, M. Rezler, W. Lee, P. Jasinski, E. Dziabaszewska, E. Nowak-Markwitz, D. Kalyon, M. Zaborowski, M. Iwanicki

This study shows that extracellular matrix (ECM) concentration modulates outgrowth formation in ovarian cancer cells by altering physical properties like elasticity and fibrous network thickness.

bioRxiv · Jan 30, 2022Cancer Biology

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Y. Lee, P. Wiriyasermkul, C. Jin, L. Quan, R. Ohgaki, S. Okuda, T. Kusakizako, T. Nishizawa, K. Oda, R. Ishitani, T. Yokoyama, T. Nakane, M. Shirouzu, H. Endou, S. Nagamori, , O. Nureki

This paper reports the cryo-EM structure of the human LAT1-CD98hc heterodimer, revealing its architecture and interactions, and maps disease mutations to explain congenital disorders.

bioRxiv · Mar 14, 2019Biochemistry