Author

L. Radic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Ward· 3 shared J. L. Torres· 3 shared K. Sliepen· 3 shared M. J. van Gils· 3 shared M. Poniman· 3 shared R. W. Sanders· 3 shared D. Eggink· 2 shared D. Gideonse· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. B. Ward

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain

D. Guerra, L. Radic, M. Brinkkemper, M. Poniman, L. van der Maas, J. L. Torres, A. B. Ward, K. Sliepen, J. Schinkel, R. W. Sanders, M. J. van Gils, T. Beaumont

This study develops bispecific antibodies that target conserved regions on the SARS-CoV-2 spike protein, showing improved neutralization breadth against multiple sarbecovirus strains.

bioRxiv · May 9, 2024Microbiology

Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses

L. Radic, K. Sliepen, V. Yin, M. Brinkkemper, J. Capella-Pujol, A. I. Schriek, J. L. Torres, S. Bangaru, J. A. Burger, M. Poniman, I. Bontjer, J. H. Bouhuijs, D. Gideonse, D. Eggink, A. B. Ward, , J. Schinkel

This study shows bispecific antibodies combine the neutralizing breadth and potency of parental antibodies to neutralize SARS-CoV and SARS-CoV-2 variants, including Omicron.

bioRxiv · Nov 11, 2022Immunology

Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual

D. Guerra, T. Beaumont, L. Radic, G. Kerster, K. van der Straten, M. Yuan, J. L. Torres, W.-H. Lee, H. Liu, M. Poniman, I. Bontjer, J. A. Burger, M. Claireaux, T. G. Caniels, J. L. Snitselaar, , M. J. van Gils

This study identifies broadly neutralizing monoclonal and bispecific antibodies from a Gamma variant-infected individual that effectively neutralize multiple SARS-CoV-2 variants.

bioRxiv · Oct 14, 2022Immunology