Author

T. Beaumont

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Ward· 3 shared M. J. van Gils· 3 shared R. W. Sanders· 3 shared D. Guerra· 2 shared J. A. Burger· 2 shared J. L. Torres· 2 shared K. Sliepen· 2 shared L. Radic· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. B. Ward

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain

D. Guerra, L. Radic, M. Brinkkemper, M. Poniman, L. van der Maas, J. L. Torres, A. B. Ward, K. Sliepen, J. Schinkel, R. W. Sanders, M. J. van Gils, T. Beaumont

This study develops bispecific antibodies that target conserved regions on the SARS-CoV-2 spike protein, showing improved neutralization breadth against multiple sarbecovirus strains.

bioRxiv · May 9, 2024Microbiology

Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses

P. J. M. Brouwer, H. R. Perrett, T. Beaumont, H. Nijhuis, S. Kruijer, J. A. Burger, W.-H. Lee, H. Muller-Krauter, R. W. Sanders, T. Strecker, M. J. van Gils, A. B. Ward

This study identifies neutralizing antibody epitopes against Lassa virus GPC using electron microscopy, revealing challenges in vaccine-induced responses and opportunities for improved vaccine design.

bioRxiv · Dec 21, 2023Immunology

Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual

D. Guerra, T. Beaumont, L. Radic, G. Kerster, K. van der Straten, M. Yuan, J. L. Torres, W.-H. Lee, H. Liu, M. Poniman, I. Bontjer, J. A. Burger, M. Claireaux, T. G. Caniels, J. L. Snitselaar, , M. J. van Gils

This study identifies broadly neutralizing monoclonal and bispecific antibodies from a Gamma variant-infected individual that effectively neutralize multiple SARS-CoV-2 variants.

bioRxiv · Oct 14, 2022Immunology