Author

L. Vogt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

A. E. Neele· 2 shared A. Jongejan· 2 shared F. J. Bemelman· 2 shared J. W. van der Heijden· 2 shared M. L. Hilhorst· 2 shared P. D. Moerland· 2 shared Y. Vegting· 2 shared B. Peters· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

A. E. Neele

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis

Y. Vegting, A. Jongejan, A. E. Neele, N. Claessen, G. Sela, K. H. Prange, J. Kers, J. J. Roelofs, J. W. van der Heijden, O. J. de Boer, E. B. Remmerswaal, L. Vogt, F. J. Bemelman, M. P. de Winther, P. D. Moerland, M. L. Hilhorst

This paper identifies specific macrophage subsets in ANCA-associated glomerulonephritis that drive inflammation and fibrosis, suggesting therapeutic targets.

bioRxiv · Mar 13, 2024 · PreprintImmunology

Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsets

Y. Vegting, K. M. Hanford, A. Jongejan, G. R. Gajadin, M. Versloot, N. D. van der Bom-Baylon, T. Dekker, E. L. Penne, J. W. van der Heijden, E. Houben, F. J. Bemelman, A. E. Neele, P. D. Moerland, L. Vogt, J. Kroon, M. L. Hilhorst

This study identifies distinct monocyte phenotypes and gene expression patterns in ANCA-associated vasculitis serotypes, linking them to cardiovascular risk.

bioRxiv · Jan 16, 2024Immunology

Phenotyping in the era of genomics: MaTrics a digital character matrix to document mammalian phenotypic traits coded numerically

C. Stefen, F. Wagner, M. Asztalos, P. Giere, P. Grobe, M. Hiller, R. Hofmann, M. Jaehde, U. Laechele, T. Lehmann, S. Ortmann, B. Peters, I. Ruf, C. Schiffmann, N. Thier, , H. Stuckas

MaTrics provides a digital matrix of mammalian phenotypes linked to genomes, highlighting knowledge gaps and enabling genomic-phenomic comparisons.

bioRxiv · Jan 17, 2021 · PreprintZoology

Mutant-selective Degradation by BRAF-targeting PROTACs

S. Alabi, S. Jaime-Figueroa, Z. Yao, Y. Gao, J. Hines, K. . T. G. Samarasinghe, L. Vogt, N. Rosen, C. M. Crews

This study develops BRAF-targeting PROTACs that degrade all BRAF mutants at sub-nanomolar concentrations while sparing wild-type RAF family members, showing in vivo efficacy and mechanistic insights.

bioRxiv · Aug 10, 2020Cancer Biology