Author

Y. Vegting

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. E. Neele· 2 shared A. Jongejan· 2 shared C. J. Rosen· 2 shared F. J. Bemelman· 2 shared J. W. van der Heijden· 2 shared L. Vogt· 2 shared M. L. Hilhorst· 2 shared P. D. Moerland· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. E. Neele

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis

Y. Vegting, A. Jongejan, A. E. Neele, N. Claessen, G. Sela, K. H. Prange, J. Kers, J. J. Roelofs, J. W. van der Heijden, O. J. de Boer, E. B. Remmerswaal, L. Vogt, F. J. Bemelman, M. P. de Winther, P. D. Moerland, M. L. Hilhorst

This paper identifies specific macrophage subsets in ANCA-associated glomerulonephritis that drive inflammation and fibrosis, suggesting therapeutic targets.

bioRxiv · Mar 13, 2024 · PreprintImmunology

Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsets

Y. Vegting, K. M. Hanford, A. Jongejan, G. R. Gajadin, M. Versloot, N. D. van der Bom-Baylon, T. Dekker, E. L. Penne, J. W. van der Heijden, E. Houben, F. J. Bemelman, A. E. Neele, P. D. Moerland, L. Vogt, J. Kroon, M. L. Hilhorst

This study identifies distinct monocyte phenotypes and gene expression patterns in ANCA-associated vasculitis serotypes, linking them to cardiovascular risk.

bioRxiv · Jan 16, 2024Immunology

Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption

C.-C. Tang, C. Castro, M. J. O'Meara, S.-H. Yoon, D. J. Brooks, M. L. Bouxsein, J. d. S. Martins, J. Wang, N. S. Gray, B. Misof, P. Roschger, S. Boulin, K. Klaushofer, A. Velduis-Vlug, Y. Vegting, , M. N. Wein

The paper shows that YKL-05-099, which inhibits SIKs and CSF1R, increases bone formation without increasing bone resorption in mice.

bioRxiv · Feb 26, 2021Physiology

Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo

E. G. Estell, P. T. Le, Y. Vegting, H. Kim, R. Baron, B. Spiegelman, C. J. Rosen

This study shows irisin directly promotes osteoclast differentiation and bone resorption in vitro and in vivo, suggesting it regulates bone remodeling beyond its effects on osteoblasts.

bioRxiv · May 9, 2020Cell Biology